Synthesis and Characterization of Andrographolide Derivatives as Regulators of βAPP Processing in Human Cells
Alzheimer’s disease (AD) is a devastating neurodegenerative disorder, one of the main characteristics of which is the abnormal accumulation of amyloid peptide (Aβ) in the brain. Whereas β-secretase supports Aβ formation along the amyloidogenic processing of the β-amyloid precursor protein (βAPP), α-...
| Główni autorzy: | , , , , , , |
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| Format: | Artykuł |
| Język: | English |
| Wydane: |
MDPI AG
2021-12-01
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| Seria: | Molecules |
| Hasła przedmiotowe: | |
| Dostęp online: | https://www.mdpi.com/1420-3049/26/24/7660 |