ANKRD22 is an N-myristoylated hairpin-like monotopic membrane protein specifically localized to lipid droplets

Abstract The membrane topology and intracellular localization of ANKRD22, a novel human N-myristoylated protein with a predicted single-pass transmembrane domain that was recently reported to be overexpressed in cancer, were examined. Immunofluorescence staining of COS-1 cells transfected with cDNA...

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Bibliographic Details
Main Authors: Toshihiko Utsumi, Takuro Hosokawa, Mayu Shichita, Misato Nishiue, Natsuko Iwamoto, Haruna Harada, Aya Kiwado, Manami Yano, Motoaki Otsuka, Koko Moriya
Format: Article
Language:English
Published: Nature Portfolio 2021-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-98486-8