Nano-immunotherapy: overcoming delivery challenge of immune checkpoint therapy

Nano-immunotherapy: overcoming delivery challenge of immune checkpoint therapy

Abstract Immune checkpoint (ICP) molecules expressed on tumor cells can suppress immune responses against tumors. ICP therapy promotes anti-tumor immune responses by targeting inhibitory and stimulatory pathways of immune cells like T cells and dendritic cells (DC). The investigation into the combin...

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Bibliographic Details
Main Authors: Seyed Hossein Kiaie, Hossein Salehi-Shadkami, Mohammad Javad Sanaei, Marzieh Azizi, Mahdieh Shokrollahi Barough, Mohammad Sadegh Nasr, Mohammad Sheibani
Format: Article
Language:English
Published: BMC 2023-09-01
Series:Journal of Nanobiotechnology
Subjects:
Immune checkpoint
Nanoparticles
Chemoimmunotherapy
PD-1 and PD-L1
CTLA-4
Tumor microenvironment
Online Access:https://doi.org/10.1186/s12951-023-02083-y

Internet

https://doi.org/10.1186/s12951-023-02083-y

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