Completion of the Entire Hepatitis C Virus Life Cycle in Vero Cells Derived from Monkey Kidney

ABSTRACT A hepatitis C virus (HCV) cell culture system incorporating the JFH-1 strain and the human hepatoma cell line HuH-7 enabled the production of infectious HCV particles. Several host factors were identified as essential for HCV replication. Supplementation of these factors in nonhepatic human...

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Bibliographic Details
Main Authors: Asako Murayama, Nao Sugiyama, Takaji Wakita, Takanobu Kato
Format: Article
Language:English
Published: American Society for Microbiology 2016-07-01
Series:mBio
Online Access:https://journals.asm.org/doi/10.1128/mBio.00273-16