<i>B. abortus</i> Infection Promotes an Imbalance in the Adipocyte–Osteoblast Crosstalk Favoring Bone Resorption

<i>B. abortus</i> Infection Promotes an Imbalance in the Adipocyte–Osteoblast Crosstalk Favoring Bone Resorption

Osteoarticular injury is the most common presentation of active brucellosis in humans. Osteoblasts and adipocytes originate from mesenchymal stem cells (MSC). Since those osteoblasts are bone-forming cells, the predilection of MSC to differentiate into adipocytes or osteoblasts is a potential factor...

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Bibliographic Details
Main Authors: Rosa Nicole Freiberger, Cinthya Alicia Marcela López, Franco Agustín Sviercz, Cintia Cevallos, Alex David Guano, Patricio Jarmoluk, Jorge Quarleri, María Victoria Delpino
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:International Journal of Molecular Sciences
Subjects:
<i>Brucella</i>
adipocyte
osteoblast
IL-6
PPAR-γ
RUNX-2
Online Access:https://www.mdpi.com/1422-0067/24/6/5617

Internet

https://www.mdpi.com/1422-0067/24/6/5617

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