Assessing the validity of asthma associations for eight candidate genes and age at diagnosis effects.

Assessing the validity of asthma associations for eight candidate genes and age at diagnosis effects.

Before the advent of genome-wide association studies (GWAS), ADAM33, ADRB2, CD14, MS4A2 (alias FCER1B), IL13, IL4, IL4R, and TNF constituted the most replicated non-HLA candidate genes with asthma and related traits. However, except for the IL13-IL4 region, none of these genes have been found in clo...

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Bibliographic Details
Main Authors: María Pino-Yanes, Almudena Corrales, José Cumplido, Paloma Poza, Inmaculada Sánchez-Machín, Anselmo Sánchez-Palacios, Javier Figueroa, Orlando Acosta-Fernández, Nisa Buset, José Carlos García-Robaina, Mariano Hernández, Jesús Villar, Teresa Carrillo, Carlos Flores
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3767824?pdf=render

Internet

http://europepmc.org/articles/PMC3767824?pdf=render

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