8-Methoxyflindersine-Induced Apoptosis and Cell Cycle Disorder Involving MAPK Signaling Activation in Human Colorectal Cancer Cells

8-Methoxyflindersine-Induced Apoptosis and Cell Cycle Disorder Involving MAPK Signaling Activation in Human Colorectal Cancer Cells

Colorectal cancer (CRC) is one of the most common malignant tumors with a high lethal rate globally, and novel strategies for its prevention and therapy are urgently needed. In our previous work, 8-methoxyflindersine (8-MF), a quinoline alkaloid, was isolated from the Dictamni cortex, and its bioact...

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Bibliographic Details
Main Authors: Dianbao Zhang, Yunmei Fu, Ying Liu, Yifan Wu, Jiayu Chen, Luting Zhang, Rui Wang, Zaixing Chen, Tao Liu
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:International Journal of Molecular Sciences
Subjects:
8-methoxyflindersine
colorectal cancer
apoptosis
cell cycle
MAPK signaling
Online Access:https://www.mdpi.com/1422-0067/24/9/8039

Internet

https://www.mdpi.com/1422-0067/24/9/8039

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