Malignant transformation in a defined genetic background: proteome changes displayed by 2D-PAGE

<p>Abstract</p> <p>Background</p> <p>Cancer arises from normal cells through the stepwise accumulation of genetic alterations. Cancer development can be studied by direct genetic manipulation within experimental models of tumorigenesis. Thereby, confusion by the genetic...

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Bibliographic Details
Main Authors: Vogiatzi Fotini, Pütz Stephanie M, Stiewe Thorsten, Sickmann Albert
Format: Article
Language:English
Published: BMC 2010-09-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/9/1/254