Imaging Aβ and tau in early stage Alzheimer’s disease with [18F]AV45 and [18F]AV1451

Imaging Aβ and tau in early stage Alzheimer’s disease with [18F]AV45 and [18F]AV1451

Abstract Background AD is a progressive neurodegenerative disorder that is associated with the accumulation of two different insoluble protein aggregates, Aβ plaques and hyperphosphorylated tau. This study aimed to investigate the optimal acquisition and quantification of [18F]AV45 and [18F]AV1451 t...

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Bibliographic Details
Main Authors: Azadeh Firouzian, Alex Whittington, Graham E. Searle, Ivan Koychev, Giovanna Zamboni, Simon Lovestone, Roger N. Gunn, on behalf of the Deep and Frequent Phenotyping study team
Format: Article
Language:English
Published: SpringerOpen 2018-03-01
Series:EJNMMI Research
Subjects:
Alzheimer’s disease
PET
Amyloid
Tau
Modelling
Online Access:http://link.springer.com/article/10.1186/s13550-018-0371-y

Internet

http://link.springer.com/article/10.1186/s13550-018-0371-y

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