Pine needles attenuate receptor activator for nuclear factor-B ligand (RANKL)-induced trabecular bone loss by inhibiting osteoclast differentiation

Background: The leaf of Pinus densiflora known as pine needles has been used to treat vascular disease, gastrointestinal diseases, and urinary diseases in traditional medicine. We evaluated anti-osteoporotic effect of water extract of Pinus densiflora (WEPN) on acute bone loss and osteoclastogenesis...

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Bibliographic Details
Main Authors: Ki-Shuk Shim, Jin Yeul Ma
Format: Article
Language:English
Published: Elsevier 2018-12-01
Series:Integrative Medicine Research
Online Access:http://www.sciencedirect.com/science/article/pii/S2213422018301653