Ebola virus triggers receptor tyrosine kinase-dependent signaling to promote the delivery of viral particles to entry-conducive intracellular compartments.

Ebola virus triggers receptor tyrosine kinase-dependent signaling to promote the delivery of viral particles to entry-conducive intracellular compartments.

Filoviruses, such as the Ebola virus (EBOV) and Marburg virus (MARV), are causative agents of sporadic outbreaks of hemorrhagic fevers in humans. To infect cells, filoviruses are internalized via macropinocytosis and traffic through the endosomal pathway where host cathepsin-dependent cleavage of th...

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Bibliografische gegevens
Hoofdauteurs: Corina M Stewart, Alexandra Phan, Yuxia Bo, Nicholas D LeBlond, Tyler K T Smith, Geneviève Laroche, Patrick M Giguère, Morgan D Fullerton, Martin Pelchat, Darwyn Kobasa, Marceline Côté
Formaat: Artikel
Taal:English
Gepubliceerd in: Public Library of Science (PLoS) 2021-01-01
Reeks:PLoS Pathogens
Online toegang:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1009275&type=printable

Internet

https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1009275&type=printable

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