Poly(ε-Caprolactone)/Poly(Glycerol Sebacate) Composite Nanofibers Incorporating Hydroxyapatite Nanoparticles and Simvastatin for Bone Tissue Regeneration and Drug Delivery Applications

Poly(ε-Caprolactone)/Poly(Glycerol Sebacate) Composite Nanofibers Incorporating Hydroxyapatite Nanoparticles and Simvastatin for Bone Tissue Regeneration and Drug Delivery Applications

Herein, we report a drug eluting scaffold composed of a composite nanofibers of poly(ε-caprolactone) (PCL) and poly(glycerol sebacate) (PGS) loaded with Hydroxyapatite nanoparticles (HANPs) and simvastatin (SIM) mimicking the bone extracellular matrix (ECM) to improve bone cell proliferation and reg...

Full description

Bibliographic Details
Main Authors: Abdelrahman I. Rezk, Kyung-Suk Kim, Cheol Sang Kim
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Polymers
Subjects:
electrospinning
biomaterial
composite nanofiber
drug delivery
bone tissue regeneration
Online Access:https://www.mdpi.com/2073-4360/12/11/2667

Internet

https://www.mdpi.com/2073-4360/12/11/2667

Similar Items