Web-based application for predicting the potential target phenotype for recombinant human thrombomodulin therapy in patients with sepsis: analysis of three multicentre registries

Web-based application for predicting the potential target phenotype for recombinant human thrombomodulin therapy in patients with sepsis: analysis of three multicentre registries

Abstract A recent randomised controlled trial failed to demonstrate a beneficial effect of recombinant human thrombomodulin (rhTM) on sepsis. However, there is still controversy in the effects of rhTM for sepsis due to the heterogeneity of the study population. We previously identified patients with...

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Bibliographic Details
Main Authors: Tadahiro Goto, Daisuke Kudo, Ryo Uchimido, Mineji Hayakawa, Kazuma Yamakawa, Toshikazu Abe, Atsushi Shiraishi, Shigeki Kushimoto
Format: Article
Language:English
Published: BMC 2022-05-01
Series:Critical Care
Subjects:
Recombinant human thrombomodulin
Sepsis
Phenotype
Prediction model
Coagulopathy
Online Access:https://doi.org/10.1186/s13054-022-04020-1

Internet

https://doi.org/10.1186/s13054-022-04020-1

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