Change in prevalence and molecular characteristics of isoniazid-resistant tuberculosis over a 10-year period in China

Change in prevalence and molecular characteristics of isoniazid-resistant tuberculosis over a 10-year period in China

Abstract Background Isoniazid (INH) represents the cornerstone for the treatment of cases infected with Mycobacterium tuberculosis (MTB) strains. Several molecular mechanisms have been shown to be the major causes for INH resistance, while the dynamic change of mutations conferring INH resistance am...

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Bibliographic Details
Main Authors: Fengmin Huo, Jie Lu, Zhaojing Zong, Wei Jing, Jin Shi, Yifeng Ma, Lingling Dong, Liping Zhao, Yufeng Wang, Hairong Huang, Yu Pang
Format: Article
Language:English
Published: BMC 2019-08-01
Series:BMC Infectious Diseases
Subjects:
Tuberculosis
Isoniazid
Drug resistance
inhA
Protionamide
Online Access:http://link.springer.com/article/10.1186/s12879-019-4333-4

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http://link.springer.com/article/10.1186/s12879-019-4333-4

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