Early protective effect of a (“pan”) coronavirus vaccine (PanCoVac) in Roborovski dwarf hamsters after single-low dose intranasal administration

Early protective effect of a (“pan”) coronavirus vaccine (PanCoVac) in Roborovski dwarf hamsters after single-low dose intranasal administration

IntroductionThe coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has highlighted the danger posed by human coronaviruses. Rapid emergence of immunoevasive variants and waning antiviral immunity decrease the effect of the currently av...

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Bibliographic Details
Main Authors: Mohammed O. Abdelaziz, Martin J. Raftery, Julian Weihs, Olivia Bielawski, Richard Edel, Julia Köppke, Daria Vladimirova, Julia M. Adler, Theresa Firsching, Anne Voß, Achim D. Gruber, Luca V. Hummel, Ivan Fernandez Munoz, Francesca Müller-Marquardt, Gerald Willimsky, Nooran S. Elleboudy, Jakob Trimpert, Günther Schönrich
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-07-01
Series:Frontiers in Immunology
Subjects:
universal COVID-19 vaccine
coronaviruses
multi-epitope vaccine
T cell epitopes
pan-coronavirus vaccine
dwarf hamster COVID-19 model
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1166765/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1166765/full

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