Do gabapentin or pregabalin directly modulate the µ receptor?

Background Pregabalin and gabapentin improve neuropathic pain symptoms but there are emerging concerns regarding their misuse. This is more pronounced among patients with substance use disorder, particularly involving opioids. Co-ingestion of gabapentinoids with opioids is increasingly identified in...

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Autors principals: Preeti Manandhar, Bridin Patricia Murnion, Natasha L. Grimsey, Mark Connor, Marina Santiago
Format: Article
Idioma:English
Publicat: PeerJ Inc. 2021-04-01
Col·lecció:PeerJ
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Accés en línia:https://peerj.com/articles/11175.pdf