Dissecting the shared genetic architecture between Alzheimer’s disease and frailty: a cross-trait meta-analyses of genome-wide association studies

Dissecting the shared genetic architecture between Alzheimer’s disease and frailty: a cross-trait meta-analyses of genome-wide association studies

Introduction: Frailty is the most common medical condition affecting the aging population, and its prevalence increases in the population aged 65 or more. Frailty is commonly diagnosed using the frailty index (FI) or frailty phenotype (FP) assessments. Observational studies have indicated the associ...

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Bibliographic Details
Main Authors: Nitesh Enduru, Brisa S. Fernandes, Zhongming Zhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-04-01
Series:Frontiers in Genetics
Subjects:
frailty index
frailty phenotype
GWAS
colocalization
Mendelian randomization
genetic correlation
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2024.1376050/full

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https://www.frontiersin.org/articles/10.3389/fgene.2024.1376050/full

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