Non-Productive Infection of Glial Cells with SARS-CoV-2 in Hamster Organotypic Cerebellar Slice Cultures

Non-Productive Infection of Glial Cells with SARS-CoV-2 in Hamster Organotypic Cerebellar Slice Cultures

The numerous neurological syndromes associated with COVID-19 implicate an effect of viral pathogenesis on neuronal function, yet reports of direct SARS-CoV-2 infection in the brain are conflicting. We used a well-established organotypic brain slice culture to determine the permissivity of hamster br...

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Bibliographic Details
Main Authors: Lise Lamoureux, Babu Sajesh, Jessy A. Slota, Sarah J. Medina, Matthew Mayor, Kathy L. Frost, Bryce Warner, Kathy Manguiat, Heidi Wood, Darwyn Kobasa, Stephanie A. Booth
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Viruses
Subjects:
SARS-CoV-2
COVID-19
brain
organotypic culture
astrocytes
microglia
Online Access:https://www.mdpi.com/1999-4915/14/6/1218

Internet

https://www.mdpi.com/1999-4915/14/6/1218

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