Interactions of the chemokines CXCL11 and CXCL12 in human tumor cells

Abstract Background The chemokines, CXCL12 and CXCL11, are upregulated in tumors from many organs and control their progression. CXCL12 and CXCL11 affect tumor cell functions by either binding their prime receptors, CXCR4 and CXCR3, respectively, and/or CXCR7 as a common second chemokine receptor. I...

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Bibliographic Details
Main Authors: Christian Koch, Nina Charlotte Fischer, Malte Puchert, Jürgen Engele
Format: Article
Language:English
Published: BMC 2022-12-01
Series:BMC Cancer
Subjects:
Online Access:https://doi.org/10.1186/s12885-022-10451-4