Interactions of the chemokines CXCL11 and CXCL12 in human tumor cells

Abstract Background The chemokines, CXCL12 and CXCL11, are upregulated in tumors from many organs and control their progression. CXCL12 and CXCL11 affect tumor cell functions by either binding their prime receptors, CXCR4 and CXCR3, respectively, and/or CXCR7 as a common second chemokine receptor. I...

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Autori principali: Christian Koch, Nina Charlotte Fischer, Malte Puchert, Jürgen Engele
Natura: Articolo
Lingua:English
Pubblicazione: BMC 2022-12-01
Serie:BMC Cancer
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Accesso online:https://doi.org/10.1186/s12885-022-10451-4