Comparative effectiveness of adding delamanid to a multidrug-resistant tuberculosis regimen comprised of three drugs likely to be effective.

Comparative effectiveness of adding delamanid to a multidrug-resistant tuberculosis regimen comprised of three drugs likely to be effective.

Clarity about the role of delamanid in longer regimens for multidrug-resistant TB is needed after discordant Phase IIb and Phase III randomized controlled trial results. The Phase IIb trial found that the addition of delamanid to a background regimen hastened culture conversion; the results of the P...

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Bibliographic Details
Main Authors: Carly A Rodriguez, Sara Lodi, C Robert Horsburgh, Carole D Mitnick, Mathieu Bastard, Helena Huerga, Uzma Khan, Michael Rich, Kwonjune J Seung, Sidney Atwood, Md Manzur-Ul-Alam, Nara Melikyan, Stephanie Mpinda, Zaw Myint, Yugandran Naidoo, Ofelya Petrosyan, Naseem Salahuddin, Samreen Sarfaraz, Stalz Charles Vilbrun, Kalkidan Yae, Jay Achar, Saman Ahmed, Elena Algozhina, Jude Beauchamp, Sara de Guadelupe Perea Moreno, Munara Gulanbaeva, Marika Gergedava, Cut Yulia Indah Sari, Catherine Hewison, Palwasha Khan, Molly F Franke
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-01-01
Series:PLOS Global Public Health
Online Access:https://doi.org/10.1371/journal.pgph.0000818

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https://doi.org/10.1371/journal.pgph.0000818

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