IQGAP1 activates PLC‐δ1 by direct binding and moving along microtubule with DLC‐1 to cell surface

IQGAP1 activates PLC‐δ1 by direct binding and moving along microtubule with DLC‐1 to cell surface

Abstract Phospholipase C (PLC)‐δ1, activated by p122RhoGTPase‐activating protein (GAP)/deleted in liver cancer‐1 (p122RhoGAP/DLC‐1), contributes to the coronary spastic angina (CSA) pathogenesis. The present study aims to further investigate the p122RhoGAP/DLC‐1 protein. We examined molecules assist...

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Bibliographic Details
Main Authors: Makoto Tanaka, Tomohiro Osanai, Yoshimi Homma, Kenji Hanada, Ken Okumura, Hirofumi Tomita
Format: Article
Language:English
Published: Wiley 2019-08-01
Series:FASEB BioAdvances
Subjects:
acetylcholine
coronary spastic angina
IQ motif‐containing GTPase‐activating protein 1
p122RhoGTPase‐activating protein (GAP)/deleted in liver cancer‐1
phospholipase C
Online Access:https://doi.org/10.1096/fba.2019-00020

Internet

https://doi.org/10.1096/fba.2019-00020

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