ApoE Lipidation as a Therapeutic Target in Alzheimer’s Disease

Apolipoprotein E (<i>APOE</i>) is the major cholesterol carrier in the brain, affecting various normal cellular processes including neuronal growth, repair and remodeling of membranes, synaptogenesis, clearance and degradation of amyloid β (Aβ) and neuroinflammation. In humans, the <i...

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Bibliographic Details
Main Authors: Maria Fe Lanfranco, Christi Anne Ng, G. William Rebeck
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/21/17/6336