Performance of Cardiotropic rAAV Vectors Is Dependent on Production Method

Gene therapy is making significant impact on a modest, yet growing, number of human diseases. Justifiably, the preferred viral vector for clinical use is that based on recombinant adeno-associated virus (rAAV). There is a need to scale up rAAV vector production with the transition from pre-clinical...

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Bibliographic Details
Main Authors: Renuka Rao, Melad Farraha, Grant J. Logan, Sindhu Igoor, Cindy Y. Kok, James J. H. Chong, Ian E. Alexander, Eddy Kizana
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/14/8/1623