Inhibitory Actions of Tropeines on the α3 Glycine Receptor Function

Inhibitory Actions of Tropeines on the α3 Glycine Receptor Function

Glycine receptors (GlyRs) are chloride-permeable pentameric ligand-gated ion channels. The inhibitory activity of GlyRs is essential for many physiological processes, such as motor control and respiration. In addition, several pathological states, such as hyperekplexia, epilepsy, and chronic pain, a...

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Bibliographic Details
Main Authors: Victoria P. San Martín, Carlos F. Burgos, Ana M. Marileo, Cesar O. Lara, Anggelo Sazo, Jorge Fuentealba, Leonardo Guzmán, Patricio A. Castro, Luis G. Aguayo, Gustavo Moraga-Cid, Gonzalo E. Yévenes
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Pharmacology
Subjects:
glycine receptor
tropeines
modulation
ligand-gated ion channels
electrophysiology
molecular docking
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.00331/full

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https://www.frontiersin.org/article/10.3389/fphar.2019.00331/full

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