Evolution of genetic markers for drug resistance after the introduction of dihydroartemisinin–piperaquine as first-line anti-malarial treatment for uncomplicated falciparum malaria in Indonesia

Evolution of genetic markers for drug resistance after the introduction of dihydroartemisinin–piperaquine as first-line anti-malarial treatment for uncomplicated falciparum malaria in Indonesia

Abstract Background Dihydroartemisinin–piperaquine has been Indonesia’s first-line anti-malarial treatment since 2008. Annual therapeutic efficacy studies (TES) done in the last 12 years showed continued high treatment efficacy in uncomplicated Plasmodium falciparum malaria. Although these studies d...

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Bibliographic Details
Main Authors: Farindira Vesti Rahmasari, Puji Budi Setia Asih, Ismail Ekoprayitno Rozi, Suradi Wangsamuda, Rifqi Risandi, Farahana Kresno Dewayanti, Dendi Hadi Permana, Lepa Syahrani, Helen Dewi Prameswari, Herdiana H. Basri, Maria Dorina G. Bustos, Prakaykaew Charunwatthana, Arjen M. Dondorp, Mallika Imwong, Din Syafruddin
Format: Article
Language:English
Published: BMC 2023-08-01
Series:Malaria Journal
Subjects:
Plasmodium falciparum
Resistance
Pfk13
Pfmdr1
Pfcrt
Pfpm2/3
Online Access:https://doi.org/10.1186/s12936-023-04658-4

Internet

https://doi.org/10.1186/s12936-023-04658-4

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