SKP2- and OTUD1-regulated non-proteolytic ubiquitination of YAP promotes YAP nuclear localization and activity
Regulation of Yes-associated protein (YAP) through the Hippo pathway is well established, but its Hippo-independent regulation remains to be elucidated. Here, the authors show that non-proteolytic ubiquitination presents another means of YAP regulation, promoting its nuclear localization and activit...
Auteurs principaux: | , , , , , , , , , , , , , , , , |
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Format: | Article |
Langue: | English |
Publié: |
Nature Portfolio
2018-06-01
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Collection: | Nature Communications |
Accès en ligne: | https://doi.org/10.1038/s41467-018-04620-y |