The Feasibility of Metagenomic Next-Generation Sequencing to Identify Pathogens Causing Tuberculous Meningitis in Cerebrospinal Fluid

The Feasibility of Metagenomic Next-Generation Sequencing to Identify Pathogens Causing Tuberculous Meningitis in Cerebrospinal Fluid

PurposeThe application of metagenomic next-generation sequencing (mNGS) in the diagnosis of tuberculous meningitis (TBM) remains poorly characterized. Here, we retrospectively analyzed data from patients with TBM who had taken both mNGS and conventional tests including culture of Mycobacterium tuber...

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Bibliographic Details
Main Authors: Shengnan Wang, Yingli Chen, Dongmei Wang, Yongming Wu, Deqiang Zhao, Jianzhao Zhang, Huifang Xie, Yanping Gong, Ruixue Sun, Xifang Nie, Haishan Jiang, Jian Zhang, Wei Li, Guanghui Liu, Xuan Li, Kaibin Huang, Yingwei Huang, Yongjun Li, Hongzhi Guan, Suyue Pan, Yafang Hu
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Microbiology
Subjects:
cerebrospinal fluid
Mycobacterium tuberculosis
meningitis
metagenomic next-generation sequencing
early diagnosis
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.01993/full

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https://www.frontiersin.org/article/10.3389/fmicb.2019.01993/full

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