The Prophylactic and Multimodal Activity of Two Isatin Thiosemicarbazones against Alzheimer’s Disease In Vitro

Alzheimer’s disease (AD) is a multifactorial disorder strongly involving the formation of amyloid-β (Aβ) oligomers, which subsequently aggregate into the disease characteristic insoluble amyloid plaques, in addition to oxidative stress, inflammation and increased acetylcholinesterase activity. Moreo...

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Bibliographic Details
Main Authors: Barbara Mavroidi, Archontia Kaminari, Dimitris Matiadis, Dimitra Hadjipavlou-Litina, Maria Pelecanou, Athina Tzinia, Marina Sagnou
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Brain Sciences
Subjects:
Online Access:https://www.mdpi.com/2076-3425/12/6/806