The Prophylactic and Multimodal Activity of Two Isatin Thiosemicarbazones against Alzheimer’s Disease In Vitro

The Prophylactic and Multimodal Activity of Two Isatin Thiosemicarbazones against Alzheimer’s Disease In Vitro

Alzheimer’s disease (AD) is a multifactorial disorder strongly involving the formation of amyloid-β (Aβ) oligomers, which subsequently aggregate into the disease characteristic insoluble amyloid plaques, in addition to oxidative stress, inflammation and increased acetylcholinesterase activity. Moreo...

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Bibliographic Details
Main Authors:	Barbara Mavroidi, Archontia Kaminari, Dimitris Matiadis, Dimitra Hadjipavlou-Litina, Maria Pelecanou, Athina Tzinia, Marina Sagnou
Format:	Article
Language:	English
Published:	MDPI AG 2022-06-01
Series:	Brain Sciences
Subjects:	isatin thiosemicarbazones Akt GSK-3β Aβ cytotoxicity acetylcholinesterase inhibitors
Online Access:	https://www.mdpi.com/2076-3425/12/6/806

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