Depletion of CUL4B in macrophages ameliorates diabetic kidney disease via miR-194-5p/ITGA9 axis

Depletion of CUL4B in macrophages ameliorates diabetic kidney disease via miR-194-5p/ITGA9 axis

Summary: Diabetic kidney disease (DKD) is the most prevalent chronic kidney disease. Macrophage infiltration in the kidney is critical for the progression of DKD. However, the underlying mechanism is far from clear. Cullin 4B (CUL4B) is the scaffold protein in CUL4B-RING E3 ligase complexes. Previou...

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Bibliographic Details
Main Authors: Shiqi Jin, Yu Song, Li Zhou, Wei Jiang, Liping Qin, Yufeng Wang, Ruiqi Yu, Yuting Liu, Yujie Diao, Fan Zhang, Kaixuan Liu, Peishan Li, Huili Hu, Baichun Jiang, Wei Tang, Fan Yi, Yaoqin Gong, Guangyi Liu, Gongping Sun
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Cell Reports
Subjects:
CP: Immunology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723005612

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http://www.sciencedirect.com/science/article/pii/S2211124723005612

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