Information sharing in high-dimensional gene expression data for improved parameter estimation in concentration-response modelling.

In toxicological concentration-response studies, a frequent goal is the determination of an 'alert concentration', i.e. the lowest concentration where a notable change in the response in comparison to the control is observed. In high-throughput gene expression experiments, e.g. based on mi...

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Bibliographic Details
Main Authors: Franziska Kappenberg, Jörg Rahnenführer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0293180&type=printable