Detection and Management of Geographic Disparities in the TOPCAT Trial

Detection and Management of Geographic Disparities in the TOPCAT Trial

TOPCAT (Treatment of Preserved Cardiac Function Heart Failure with an Aldosterone Antagonist Trial) was a multinational clinical trial of 3,445 heart failure with preserved ejection fraction patients that enrolled in 233 sites in 6 countries in North America, Eastern Europe, and South America. Patie...

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Bibliographic Details
Main Authors: Michael R. Bristow, MD, PhD, Jorge Silva Enciso, MD, Bernard J. Gersh, MB, ChB, DPhil, Christine Grady, RN, PhD, Madeline Murguia Rice, PhD, Steven Singh, MD, George Sopko, MD, MPH, Robin Boineau, MD, MA, Yves Rosenberg, MD, MPH, Barry H. Greenberg, MD
Format: Article
Language:English
Published: Elsevier 2016-04-01
Series:JACC: Basic to Translational Science
Subjects:
clinical trials
data and safety monitoring of clinical trials
geographic inconsistencies in clinical trials
heart failure with preserved ejection fraction
multinational clinical trials
spironolactone
Online Access:http://www.sciencedirect.com/science/article/pii/S2452302X16000346

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http://www.sciencedirect.com/science/article/pii/S2452302X16000346

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