Identification of a venetoclax-resistance prognostic signature base on 6-senescence genes and its clinical significance for acute myeloid leukemia

Identification of a venetoclax-resistance prognostic signature base on 6-senescence genes and its clinical significance for acute myeloid leukemia

BackgroundSatisfactory responses can be obtained for acute myeloid leukemia (AML) treated by Venetoclax (VEN)-based therapy. However, there are still quite a few AML patients (AMLs) resistant to VEN, and it is critical to understand whether VEN-resistance is regulated by senescence.MethodsHere, we e...

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Bibliographic Details
Main Authors: Peng Ke, Jundan Xie, Ting Xu, Meiyu Chen, Yusha Guo, Ying Wang, Huiying Qiu, Depei Wu, Zhao Zeng, Suning Chen, Xiebing Bao
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Oncology
Subjects:
venetoclax resistance
senescence
prognosis
acute myeloid leukemia
immunotherapy
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1302356/full

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https://www.frontiersin.org/articles/10.3389/fonc.2023.1302356/full

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