Genetic and Non-Genetic Mechanisms of Resistance to BCR Signaling Inhibitors in B Cell Malignancies

The approval of BTK and PI3K inhibitors (ibrutinib, idelalisib) represents a revolution in the therapy of B cell malignancies such as chronic lymphocytic leukemia (CLL), mantle-cell lymphoma (MCL), diffuse large B cell lymphoma (DLBCL), follicular lymphoma (FL), or Waldenström’s macroglobulinemia (W...

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Podrobná bibliografie
Hlavní autoři: Laura Ondrisova, Marek Mraz
Médium: Článek
Jazyk:English
Vydáno: Frontiers Media S.A. 2020-10-01
Edice:Frontiers in Oncology
Témata:
On-line přístup:https://www.frontiersin.org/articles/10.3389/fonc.2020.591577/full