The compound losartan cream inhibits scar formation via TGF-β/Smad pathway

Abstract The role of angiotensin receptor blocker in wound healing and cutaneous fibrosis has become a hotspot in recent years. We have developed a losartan cream that is comparable to triamcinolone ointment in inhibiting scarring. Considering the effects of chitosan and asiaticoside on wound healin...

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Bibliographic Details
Main Authors: Wan-Yi Zhao, Li-Yun Zhang, Zheng-Cai Wang, Qing-Qing Fang, Xiao-Feng Wang, Yong-Zhong Du, Bang-Hui Shi, Dong Lou, Gui-Da Xuan, Wei-Qiang Tan
Format: Article
Language:English
Published: Nature Portfolio 2022-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-17686-y