PEG-conjugated bovine haemoglobin enhances efficiency of chemotherapeutic agent doxorubicin with alleviating DOX-induced splenocardiac toxicity in the breast cancer

PEG-conjugated bovine haemoglobin enhances efficiency of chemotherapeutic agent doxorubicin with alleviating DOX-induced splenocardiac toxicity in the breast cancer

AbstractDoxorubicin (DOX) is an effective chemotherapeutic agent widely used for cancer treatment. However, hypoxia in tumour tissue and obvious adverse effects particularly cardiotoxicity restricts the clinical usage of DOX. Our study is based on the co-administration of haemoglobin-based oxygen ca...

Full description

Bibliographic Details
Main Authors: Bingting Li, Jun Zhang, Ning Ma, Weidan Li, Guoxing You, Gan Chen, Lian Zhao, Quan Wang, Hong Zhou
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Artificial Cells, Nanomedicine, and Biotechnology
Subjects:
Doxorubicin
tumour hypoxia
HBOCs
cardiotoxicity
splenic toxicity
Online Access:https://www.tandfonline.com/doi/10.1080/21691401.2023.2176865

Internet

https://www.tandfonline.com/doi/10.1080/21691401.2023.2176865

Similar Items