Binding Interaction of Betulinic Acid to α-Glucosidase and Its Alleviation on Postprandial Hyperglycemia

Binding Interaction of Betulinic Acid to α-Glucosidase and Its Alleviation on Postprandial Hyperglycemia

Inhibiting the intestinal α-glucosidase can effectively control postprandial hyperglycemia for type 2 diabetes mellitus (T2DM) treatment. In the present study, we reported the binding interaction of betulinic acid (BA), a pentacyclic triterpene widely distributed in nature, on α-glucosidase and its...

Full description

Bibliographic Details
Main Authors: Shaodan Chen, Bing Lin, Jiangyong Gu, Tianqiao Yong, Xiong Gao, Yizhen Xie, Chun Xiao, Janis Yaxian Zhan, Qingping Wu
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Molecules
Subjects:
betulinic acid
α-glucosidase
inhibition mechanism
postprandial hyperglycemia
synergistic effect
Online Access:https://www.mdpi.com/1420-3049/27/8/2517

Internet

https://www.mdpi.com/1420-3049/27/8/2517

Similar Items