NK Cells Regulate CD8+ T Cell Mediated Autoimmunity

NK Cells Regulate CD8+ T Cell Mediated Autoimmunity

Elucidating key factors that regulate immune-mediated pathology in vivo is critical for developing improved strategies to treat autoimmune disease and cancer. NK cells can exhibit regulatory functions against CD8+ T cells following viral infection. Here we show that while low doses of lymphocytic ch...

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Bibliographic Details
Main Authors: Philipp A. Lang, Sarah Q. Crome, Haifeng C. Xu, Karl S. Lang, Laurence Chapatte, Elissa K. Deenick, Melanie Grusdat, Aleksandra A. Pandyra, Vitaly I. Pozdeev, Ruifeng Wang, Tobias A. W. Holderried, Harvey Cantor, Andreas Diefenbach, Alisha R. Elford, David R. McIlwain, Mike Recher, Dieter Häussinger, Tak W. Mak, Pamela S. Ohashi
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
CTL
LCMV
IFN-α
autoimmunity
pathology
Online Access:https://www.frontiersin.org/article/10.3389/fcimb.2020.00036/full

Internet

https://www.frontiersin.org/article/10.3389/fcimb.2020.00036/full

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