Granulocyte colony-stimulating factor directly acts on mouse lymphoid-biased but not myeloid-biased hematopoietic stem cells

Granulocyte colony-stimulating factor (G-CSF) is widely used in clinical settings to mobilize hematopoietic stem cells (HSCs) into the circulation for HSC harvesting and transplantation. However, whether G-CSF directly stimulates HSCs to change their cell cycle state and fate is controversial. HSCs...

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Bibliographic Details
Main Authors: Miner Xie, Shanshan Zhang, Fang Dong, Qingyun Zhang, Jinhong Wang, Chenchen Wang, Caiying Zhu, Sen Zhang, Bingqing Luo, Peng Wu, Hideo Ema
Format: Article
Language:English
Published: Ferrata Storti Foundation 2020-02-01
Series:Haematologica
Online Access:https://haematologica.org/article/view/9657