Mapping cell type-specific transcriptional enhancers using high affinity, lineage-specific Ep300 bioChIP-seq

Mapping cell type-specific transcriptional enhancers using high affinity, lineage-specific Ep300 bioChIP-seq

Understanding the mechanisms that regulate cell type-specific transcriptional programs requires developing a lexicon of their genomic regulatory elements. We developed a lineage-selective method to map transcriptional enhancers, regulatory genomic regions that activate transcription, in mice. Since...

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Bibliographic Details
Main Authors: Pingzhu Zhou, Fei Gu, Lina Zhang, Brynn N Akerberg, Qing Ma, Kai Li, Aibin He, Zhiqiang Lin, Sean M Stevens, Bin Zhou, William T Pu
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-01-01
Series:eLife
Subjects:
transcriptional enhancer
endothelial cell
angiogenesis
p300
Online Access:https://elifesciences.org/articles/22039

Internet

https://elifesciences.org/articles/22039

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