Retention Rates of Genetic Therapies Based on AAV Serotypes 2 and 8 Using Different Drug-Delivery Materials

Retention Rates of Genetic Therapies Based on AAV Serotypes 2 and 8 Using Different Drug-Delivery Materials

The purpose of this study was to compare the retention rate of Adeno-associated viral vector (AAV) gene therapy agents within different subretinal injection systems. The retention of AAV serotype 2-based voretigene neparvovec (VN) and a clinical-grade AAV serotype 8 vector within four different subr...

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Bibliographic Details
Main Authors: Felix F. Reichel, Peter Kiraly, Immanuel P. Seitz, M. Dominik Fischer
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:International Journal of Molecular Sciences
Subjects:
retention
AAV
gene therapy
subretinal injection
drug delivery
Online Access:https://www.mdpi.com/1422-0067/25/7/3705

Internet

https://www.mdpi.com/1422-0067/25/7/3705

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