Identification of SPRYD4 as a tumour suppressor predicts prognosis and correlates with immune infiltration in cholangiocarcinoma

Abstract Cholangiocarcinoma (CCA) is an aggressive solid tumour with a 5-year survival rate ranging from 7% to 20%. It is, therefore, urgent to identify novel biomarkers and therapeutic targets to improve the outcomes of patients with CCA. SPRY-domain containing protein 4 (SPRYD4) contains SPRY doma...

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Bibliographic Details
Main Authors: Zuyi Ma, Tiange Xie, Jia Sun, Jianchun Yu, Shanzhou Huang, Qi Zhou, Binglu Li
Format: Article
Language:English
Published: BMC 2023-05-01
Series:BMC Cancer
Subjects:
Online Access:https://doi.org/10.1186/s12885-023-10810-9