Low pathogenic avian influenza virus isolates with different levels of defective genome segments vary in pathogenicity and transmission efficiency
Abstract Defective interfering particles (DIPs) of influenza virus are generated through incorporation of highly truncated forms of genome segments, mostly those coding polymerase complex proteins (PB2, PB1, PA). Such particles are able to replicate only in the presence of a virus with the complete...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-08-01
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Series: | Veterinary Research |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13567-020-00833-6 |