Low pathogenic avian influenza virus isolates with different levels of defective genome segments vary in pathogenicity and transmission efficiency

Abstract Defective interfering particles (DIPs) of influenza virus are generated through incorporation of highly truncated forms of genome segments, mostly those coding polymerase complex proteins (PB2, PB1, PA). Such particles are able to replicate only in the presence of a virus with the complete...

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Bibliographic Details
Main Authors: Edyta Świętoń, Karolina Tarasiuk, Krzysztof Śmietanka
Format: Article
Language:English
Published: BMC 2020-08-01
Series:Veterinary Research
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13567-020-00833-6