RNA Structural Dynamics Modulate EGFR-TKI Resistance Through Controlling YRDC Translation in NSCLC Cells

RNA Structural Dynamics Modulate EGFR-TKI Resistance Through Controlling YRDC Translation in NSCLC Cells

Epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) positively affect the initial control of non-small cell lung cancer (NSCLC). Rapidly acquired resistance to EGFR-TKIs is a major hurdle in successful treatment. However, the mechanisms that control the resistance of EGFR-TKIs re...

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Bibliographic Details
Main Authors: Boyang Shi, Ke An, Yueqin Wang, Yuhan Fei, Caixia Guo, Qiangfeng Cliff Zhang, Yun-Gui Yang, Xin Tian, Quancheng Kan
Format: Article
Language:English
Published: Oxford University Press 2023-08-01
Series:Genomics, Proteomics & Bioinformatics
Subjects:
RNA structure
EGFR-TKI resistance
Non-small cell lung cancer
YRDC
ELAVL1
Online Access:http://www.sciencedirect.com/science/article/pii/S1672022922001425

Internet

http://www.sciencedirect.com/science/article/pii/S1672022922001425

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