Role of Regulatory Cells in Immune Tolerance Induction in Hemophilia A

The main complication of hemophilia A treatment is the development of neutralizing antibodies (inhibitors) against factor VIII (FVIII). Immune tolerance induction (ITI) is the prescribed treatment for inhibitor eradication, although its working mechanism remains unresolved. To clarify this mechanism...

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Bibliographic Details
Main Authors: Sarah J. Schep, Roger E. G. Schutgens, Kathelijn Fischer, Jan Voorberg, Marianne Boes
Format: Article
Language:English
Published: Wiley 2021-05-01
Series:HemaSphere
Online Access:http://journals.lww.com/10.1097/HS9.0000000000000557