Unlocking vinpocetine's oncostatic potential in early-stage hepatocellular carcinoma: A new approach to oncogenic modulation by a nootropic drug.

The development of new drugs for the inhibition of hepatocellular carcinoma (HCC) development and progression is a critical and urgent need. The median survival rate for HCC patients remains disappointingly low. Vinpocetine is a safe nootropic agent that is often used to enhance cognitive function....

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Main Authors: Osama A Mohammed, Mahmoud E Youssef, Rabab S Hamad, Mustafa Ahmed Abdel-Reheim, Lobna A Saleh, Mohannad Mohammad S Alamri, Muffarah Hamid Alharthi, Jaber Alfaifi, Masoud I E Adam, Ali M S Eleragi, Ahmed Senbel, Alshaimaa A Farrag, Assad Ali Rezigalla, Hend S El-Wakeel, Mohammed A Attia, Hussein M El-Husseiny, Tohada M Al-Noshokaty, Ahmed S Doghish, Ahmed Gaafar Ahmed Gaafar, Sameh Saber
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0312572&type=printable