Role of aquaporin-4 polarization in extracellular solute clearance

Role of aquaporin-4 polarization in extracellular solute clearance

Abstract Waste from the brain has been shown to be cleared via the perivascular spaces through the so-called glymphatic system. According to this model the cerebrospinal fluid (CSF) enters the brain in perivascular spaces of arteries, crosses the astrocyte endfoot layer, flows through the parenchyma...

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Bibliographic Details
Main Authors: Laura Bojarskaite, Sahar Nafari, Anne Katrine Ravnanger, Mina Martine Frey, Nadia Skauli, Knut Sindre Åbjørsbråten, Lena Catherine Roth, Mahmood Amiry-Moghaddam, Erlend A. Nagelhus, Ole Petter Ottersen, Inger Lise Bogen, Anna E. Thoren, Rune Enger
Format: Article
Language:English
Published: BMC 2024-03-01
Series:Fluids and Barriers of the CNS
Subjects:
AQP4
Glymphatic
Waste clearance
Astrocyte
Glia
Syntrophin
Online Access:https://doi.org/10.1186/s12987-024-00527-7

Internet

https://doi.org/10.1186/s12987-024-00527-7

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