A novel OxyR sensor and regulator of hydrogen peroxide stress with one cysteine residue in Deinococcus radiodurans.

In bacteria, OxyR is a peroxide sensor and transcription regulator, which can sense the presence of reactive oxygen species and induce antioxidant system. When the cells are exposed to H(2)O(2), OxyR protein is activated via the formation of a disulfide bond between the two conserved cysteine residu...

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Bibliographic Details
Main Authors: Huan Chen, Guangzhi Xu, Ye Zhao, Bing Tian, Huiming Lu, Xiaomin Yu, Zhenjian Xu, Nanjiao Ying, Songnian Hu, Yuejin Hua
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2225504?pdf=render