Porphyromonas gingivalis infection promotes mitochondrial dysfunction through Drp1-dependent mitochondrial fission in endothelial cells

Abstract Porphyromonas gingivalis (P. gingivalis), a key pathogen in periodontitis, has been shown to accelerate the progression of atherosclerosis (AS). However, the definite mechanisms remain elusive. Emerging evidence supports an association between mitochondrial dysfunction and AS. In our study,...

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Bibliographic Details
Main Authors: Tong Xu, Qin Dong, Yuxiao Luo, Yanqing Liu, Liang Gao, Yaping Pan, Dongmei Zhang
Format: Article
Language:English
Published: Nature Publishing Group 2021-09-01
Series:International Journal of Oral Science
Online Access:https://doi.org/10.1038/s41368-021-00134-4